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Science based longevity solutions

Cutting edge supplement formulations - made in Germany

Developed by medical doctors - with third-party lab tests

Proteomic testing platform for lifestyle and age assessment

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Move better with Hyperice

Normatec compression boots help increase circulation

Hypervolt massage guns help improve range of motion

Venom heat and massage wraps help loosen soreness

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Sleep better, perform stronger

Suitable for allergy sufferers & hypoallergenic

90 nights free sleep trial

Suitable for at home and on the go

Improve sleep

Germany’s leading B2B & B2C longevity event

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Germany’s leading B2B & B2C longevity event

100+ speakers, 4 stages, 20 workshops, 12 experiences

Performance, biotech, beauty and wellness in one place

Meet world renowned experts, exchange ideas and grow together

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Unlock Your Health Potential

Swiss-Made, Science-Backed Supplements

Rejuvenate with Clean, High-Quality Nutrition

Elevate Your Energy with Precision

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Martin Brüggemann

Hannover, Germany

Partner, Dad, Co-Founder t3n, CTO (20+ years), Espresso-Lover, Ultracycling enthusiast and Longevity Fan. CTO New Zapiens GmbH.

Guillaume Agis

Toulouse, France • 35 years

CTO @ Ikare.ai , Tech entrepreneur & biohacker

Simon Krüger

Berlin, Germany • 41 years

Love the water in summer and the mountains in winter. Father of 3. Entrepreneur. Co-founder Doctolib Germany and New Zapiens 🚀

Medical doctor & Co-Founder of the german longevity company MOLEQLAR®. Host "Beyond Lifespan Podcast". Interested in a science-backed approach to healthy aging and longevity involving nutrition, supplements and health tech.

Floris Roltsch

Boltenhagen, Germany • 33 years

Data Scientist • Co-founder LONGEVITAL • I want to maintain optimal health and performance until 60 years old and stay free from chronic disease until 90 or longer. • Built LONGEVITAL to help me and others get there by combining biomarkers & BioAge with daily feedback through effortless lifestyle tracking.

Callum Parker

San Francisco, CA, USA • 26 years

Biohacker, exercise enthusiast, KALOS. https://www.livekalos.com/ First person to hit 1000lb club and 4:30 mile same day. My favourite supplement is creatine.

Sandra

Munich, Germany • 39 years

I believe in primary prevention as a mean to counter-balance individual genetic risks. Super interested in functional medicine, but frustrated about the limited options available in Germany (anyone around in Munich? ;-) ). Medical Doctor and Molecular Biologist by training (but not providing medical services myself anymore)

Hadi Saleh

Berlin, Germany

Trained Orthopedic Surgeon Entrepreneur - CEO of CeramTec Group, a midcap German „Hidden Champion“ Since more than 9 years I have embarked on the journey to find out how I can optimize my life towards a healthy long life - striving to live to 120 years. I have a German Podcast called „Mission Gesundheit“ dealing with all topics regarding to health and have written a book with the same title.

Heiko Bartlog

Berlin, Germany • 50 years

Mentor for Vitality with special expertise in Essential Micronutrients: Measure – Plan – Optimize – repeat! With years of experience as a Project Management Consultant, Coach for Leadership and Agility, Facilitator for Co-Creation and Effectuation Expert.

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MOLEQLAR

4.7

• 40 Reviews

MOLEQLAR offers a range of high-quality supplements and lab tests designed to enhance longevity, performance, and overall well-being. Their products include a proprietary proteomic testing platform as well as Nicotinamide mononucleotide (NMN), resveratrol, spermidine, and other essential compounds aimed at supporting cellular health.

YEARS

5.0

• 2 Reviews

YEARS offers the Personal Aging Check, providing the most comprehensive knowledge about your body you have ever experienced.

BLACKROLL

4.6

• 35 Reviews

BLACKROLL offers special foam rollers, fascia tools, and exercise accessories designed to improve mobility, relieve muscle tension, and enhance sports performance and recovery. Their products are used by athletes, physical therapists, and fitness enthusiasts worldwide for (self-)massage, myofascial release, and overall movement optimization.

Nurosym

4.2

• 5 Reviews

Nurosym offers a wearable device designed to provide relief from various conditions, such as Long-COVID, PTSD, depression, and more. The device uses non-invasive neuromodulation to stimulate the vagus nerve, helping to improve overall well-being.

Polar

4.4

• 10 Reviews

Polar is a global leader in heart rate monitors, fitness trackers, and sports watches. Their products are designed to help athletes and fitness enthusiasts track their performance and achieve their fitness goals.

Eight Sleep

4.5

• 4 Reviews

Eight Sleep offers the intelligent sleep system designed to improve sleep quality through advanced technology. Their products include smart mattresses and accessories that provide personalized sleep tracking and temperature regulation.

Sunday Natural

4.6

• 134 Reviews

Sunday Natural offers natural vitamins, supplements, and vital substances to support overall health and well-being. The products address various health needs, from overall body systems to specific concerns, including age- and gender-specific topics like menopause, gut health, and immune support.

Hyperice

4.8

• 6 Reviews

Hyperice provides innovative technology to enhance muscle recovery and improve mobility.

Aware

4.5

• 22 Reviews

Aware offers an app that provides deep insights into your health by tracking vitamin D, glucose, and cholesterol levels. Their technology helps users monitor and improve their overall well-being with real-time data and personalized recommendations.

Oura

4.3

• 28 Reviews

Oura delivers cutting-edge health insights right at your fingertips—literally. This sleek Finnish-designed ring tracks sleep, recovery, and daily activity, empowering you to optimize your longevity journey and enhance overall well-being.

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Multilingualism increases life expectancy

Lifespan Extension Interventions

•

2 min read

Multilingualism increases life expectancy

Could having a sharp vocabulary extend your lifespan? A new study suggests that strong verbal fluency—basically, how quickly you can recall and use words—may predict how long you’ll live.Key Facts & FindingsBerlin aging study: Researchers tracked 516 adults (70–105 years old) for up to 18 years.Singular predictor: Verbal fluency stood out as a key indicator linked to longevity.Test of choice: One approach asked participants to name as many animals as possible in 90 seconds.Complex process: Verbal fluency relies on memory, vocabulary, and efficient mental organization—possibly mirroring whole-body health.Tandem of agingThe brain and body age in tandem; so how we express ourselves might reflect overall wellness. “You’re basically flexing multiple mental muscles at once,” said lead researcher Paolo Ghisletta. The team used new data-crunching techniques, combining them with decades-old observations, to pinpoint verbal fluency as a unique longevity signal.Stay mentally activeWhat does this mean for you? Keep learning, stay mentally active, and challenge your linguistic skills (think word puzzles or new language lessons). Future studies will dig deeper into why language agility is so powerful—and how we can harness it for longer, healthier lives. For now, talk it out—your words might just help you live longer.

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Recovery

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4 min read

How helpfull are intermittent pneumatic compression devices as the Normatec Recovery System?

Intermittent pneumatic compression (IPC) devices, exemplified by the Normatec systems such as Normatec Elite, Normatec 3 Legs or the Normatec 3 Full Body, have garnered significant attention within athletic and rehabilitation communities. These devices employ sequential, controlled pressure applied to the limbs, aiming to augment physiological processes crucial for recovery. The purported benefits include enhanced blood flow, lymphatic drainage, and mitigation of exercise-induced muscle damage (EIMD).Physiological mechanisms and theoretical benefitsThe rationale behind IPC's efficacy lies in its ability to simulate the natural muscle pump action. By applying cyclical pressure, these devices potentially facilitate the removal of metabolic waste products, such as lactate, which accumulate post-exercise. This, in turn, may attenuate delayed-onset muscle soreness (DOMS) and promote tissue repair. Furthermore, IPC may influence inflammatory responses, a key factor in muscle recovery.Evidence-based efficacy: a critical appraisalWhile the theoretical underpinnings of IPC are plausible, the empirical evidence supporting its clinical effectiveness in healthy athletic populations presents a nuanced picture. An increasing number of studies demonstrates positive effects on recovery parameters, such as reduced muscle soreness and improved blood flow.For example, a study published in ‘PLOS one’ has shown that IPC improves the flexibility and reduces oxidative stress and proteolysis markers in the muscles during recovery from heavy resistance exercises. Another study demonstrated an increasing total hemoglobin concentration and advantages in the management of muscle soreness related to physical activity. Last but not least positive effects on the endothelial function and the bloodflow have also been proven and there are clear indications that IPC cann have positive effects on gene and protein expression, that are associated with functional improvements. All in all, it seems that IPC devices can significantly improve regeneration, especially for top athletes but also for normal sportspeople. However, some investigations have yielded less conclusive results, with some failing to demonstrate statistically significant differences compared to traditional recovery modalities like massage. This discrepancy highlights the need for further research to elucidate the specific contexts in which IPC may provide tangible benefits. But let's get clear, even IPC devices only work as well as massages, this remains a significant positive effect.Psychological impact and subjective perceptionsBeyond the physiological effects, the psychological impact of IPC warrants consideration. Many users report a heightened sense of well-being and increased confidence in their recovery protocols when utilizing these devices. This subjective perception, while not directly quantifiable, may nonetheless contribute to an athlete's overall recovery experience and subsequent performance.Clinical applications and versatilityIPC devices are not exclusively utilized by athletes. Their applications extend to various clinical settings, including physical therapy and rehabilitation programs. The potential for improved circulation and reduced edema makes them valuable tools in managing certain medical conditions. However, it is crucial to acknowledge that IPC is not a panacea, and its use should be guided by healthcare professionals, particularly for individuals with pre-existing medical conditions.Possible risks and contraindicationsSome conditions may preclude the use of IPC devices, for example:Active infections: Using IPC devices over areas with active infections may exacerbate the condition.Severe edema: Individuals with significant swelling should avoid IPC devices, as they could worsen the situation.Certain cardiovascular conditions: Users with severe arterial disease, heart conditions, or other related ailments should refrain from using these devices without medical supervision. Acute deep vein thrombosis (DVT) or thrombophlebitis.Methodological considerations and future directionsThe existing body of research on IPC is not without limitations. Variations in study design, intervention protocols (e.g., pressure levels, duration), and outcome measures make it challenging to synthesize the evidence and draw definitive conclusions. Future research should prioritize standardized methodologies, larger sample sizes, and the inclusion of diverse athletic populations to provide a more comprehensive understanding of IPC's efficacy.ConclusionIntermittent pneumatic compression such as Normatec Elite, the Normatec 3 Legs, Normatec 3 Lower Body or the Normatec 3 Full Body hold promise as a recovery modality for athletes and individuals seeking enhanced well-being. Also, the theoretical benefits are well-articulated and a growing empirical evidence supports the widespread use, further research is warranted to delineate the specific contexts and parameters under which IPC can achieve the optimum result.

Lifespan Extension Interventions

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2 min read

Pressing pause on aging?

A ton of hype—and equally high hopes. What’s going onFrom high-profile Instagram influencers to billionaire investments, the quest for a “fountain of youth” is big business. US tech entrepreneur Bryan Johnson claims to swallow more than 100 pills a day, while research teams worldwide test potential “longevity” drugs—think rapamycin, metformin, senolytics, or GLP-1 receptor agonists. Key takeawaysLifestyle still reigns: Studies repeatedly show that not smoking, limiting alcohol, getting enough sleep, and eating a balanced diet can add years—even decades—to one’s life.Genes vs. pills: Many dream of a simple longevity pill, but genes and healthy habits usually have a stronger impact.Blue zones and centenarians: Places like Okinawa or Sardinia boast unusually high numbers of 100-year-olds—though skeptics argue administrative errors may inflate these stats.Money and skepticism: From NAD+ or glutathione IV drips to plasma infusions, countless “anti-aging” offers exist—but most lack solid human trial evidence. Experts warn against overstated promises.Why it mattersWhether you call it geroprotection or anti-aging, halting the aging process has gripped humanity for centuries. Billionaire-backed labs test new therapies, while social media swarms with expensive “youth-restoring” treatments. But the bottom line remains: basic healthy habits often outweigh any miracle cure.Looking ahead Extending “Health Span”: The goal isn’t just to live longer, but to live better, avoiding debilitating diseases in old age.A pill vs. ice baths?: Future meds might slow aging’s clock—though their real-world impact is yet unknown.Societal implications: Lifespans are rising, as are the years spent in poor health. Policymakers and scientists hope new therapies can compress those frail years—worth billions if proven effective. 

Supplements—when muscle gains go too far

Strength Training

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2 min read

Supplements—when muscle gains go too far

Watch your supplements! A new Canadian study just linked popular muscle-building supplements (like whey protein and creatine) to heightened risk of muscle dysmorphia—a psychological condition fueled by the relentless drive for more muscle. Could your daily shake be feeding more than just gains?Key facts and findingsBig sample: Over 2,700 adolescents and young adults took part in the national survey.Supplement stack: Whey, creatine, pre-workout—each was associated with higher muscle dysmorphia scores.Clinical red flag: Using multiple products boosted odds of hitting the clinical cutoff for muscle dysmorphia.Gender nuances: While men were bigger users overall, women showed stronger links between product use and dysmorphia symptoms.Additional context and expert insightMuscle dysmorphia (a specifier of body dysmorphic disorder) involves obsessive thoughts, intense workout regimens, and body-image struggles. Researchers note that certain supplements, especially creatine or mass gainers, might reinforce this relentless “must get bigger” mindset. Yet ironically, many users reported less “appearance intolerance,” perhaps because supplements help them feel closer to their physique goals.“This study highlights the complex ways supplements interact with body image,” says one investigator. “We need more education for younger consumers.”Looking aheadExpect more scrutiny of how these products—still loosely regulated—affect mental and physical health. Meanwhile, if you’re stacking powders and pills, keep tabs on your mindset. Balancing workouts with proper nutrition—and maybe chatting with a health professional—could help dodge the slippery slope of muscle obsession.

Testosterone and longevity: how hormone levels impact our quality and length of life

Hormone Balance

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7 min read

Testosterone and longevity: how hormone levels impact our quality and length of life

Testosterone is often seen as a symbol of masculinity, strength, and vitality. But what if I told you that this hormone also plays a crucial role for longevity in men?Indeed, low levels of testosterone were linked to a shorter life span, in a recent study (1). And, as we age, the apparent effects of testosterone on our health, mood, and well-being become even more significant.In the following, we will explore how testosterone influences longevity and what you can do to optimize your hormone levels for a longer, healthier life. What is testosterone and why does it matter? Testosterone is a vital hormone for both men and women. It is primarily produced in the testes in men, in the ovaries in women, and in the adrenal gland in both sexes. It’s crucial for muscle growth, bone density, libido, and the regulation of mood. But beyond these commonly known roles, testosterone also affects cognitive function, cardiovascular health, and metabolic processes, all of which are key players in how “well” we age.As men reach their 30s, testosterone levels begin to decline, typically by about 1% each year (2). While subtle at first, this decline can significantly affect health, leading to decreased energy, loss of muscle mass, mood fluctuations, and reduced libido. This is especially concerning given that up to 40% of men today are affected by testosterone deficiency (3).On the other hand, maintaining optimal testosterone levels has been associated with both a longer lifespan and an extended health span - that is, the number of years lived in good health (4,5). Over the past years, we have worked closely with hundreds of men to optimize their hormone levels, and the impact on key longevity markers has been strikingly clear. Let me explain in more detail:The connection between testosterone and longevity Testosterone’s influence on bodily functions has been extensively studied, and several key findings highlight its critical role in longevity: Muscle mass and metabolism: Testosterone plays a direct role in building and maintaining muscle mass. As we age, muscle loss accelerates, contributing to frailty and a decrease in overall vitality. Testosterone helps prevent this by promoting muscle protein synthesis and supporting metabolic function. This is particularly important because muscle mass is not only a sign of strength but also a key factor in metabolic health and weight management.Cardiovascular health: Testosterone also plays a crucial role in cardiovascular health. Research suggests that optimal testosterone levels help maintain healthy cholesterol levels, improve blood circulation, and even promote the production of red blood cells. Low testosterone has been associated with a higher risk of cardiovascular disease. The aforementioned recent Australian study involving nearly 25,000 men further reinforced this link, directly connecting testosterone deficiency to increased cardiovascular mortality (1).Bone health: Osteoporosis is an often overlooked condition in men. The disease is closely associated with aging, however the role of testosterone in the development of the disease is frequently underestimated. Testosterone is being aromatized to estrogen, which has a significant impact on bone density. Studies show that men with low testosterone levels tend to have lower bone mineral density and a higher risk of fractures. Ensuring adequate testosterone levels can thus help maintain bone health, reducing the risk of falls and fractures as we age.Mental health and cognitive function: Testosterone isn’t just about physical health, it also affects your mental well-being. Low levels of testosterone have been linked to depression, fatigue, and cognitive decline. On the other hand, maintaining healthy testosterone levels can improve mood, cognitive function, and overall mental clarity, helping you stay sharp well into your later years. Many of our patients report symptoms like brain fog and difficulty concentrating, which often disappear once hormonal imbalances are corrected.The downside of low testosteroneTestosterone deficiency is no longer just a condition of aging men. Today, around 20% of young men suffer from low testosterone levels, and research suggests that this trend is continuing to worsen (6). The symptoms can be wide-ranging and often impact daily life. Common complaints include:Decreased energy and motivationLower libido and sexual dysfunctionIncreased body fat and decreased muscle massPoor mood, irritability, and even depressionDifficulty concentrating or memory problemsThese symptoms not only affect quality of life but can also contribute to other health issues like obesity, diabetes, and cardiovascular disease—a well-published phenomenon. Recognizing the signs of low testosterone and addressing them early can significantly improve overall well-being.How to optimize testosterone naturallyFortunately, there are several effective ways to naturally optimize testosterone levels, supporting both health and longevity. Interestingly, the typical age-related decline (starting in the 30s for most men) is often not observed in those who maintain a healthy lifestyle and remain free from chronic diseases. To my knowledge, the most powerful strategies to sustain optimal testosterone levels include:Regular exercise: Physical activity is one of the most effective ways to ensure healthy testosterone levels. Strength training, high-intensity interval training, and aerobic exercises can all increase testosterone production. Regular exercise also helps maintain muscle mass, supports cardiovascular health, and improves metabolic function.Nutrient-rich diet: A healthy diet rich in essential nutrients is crucial for maintaining healthy testosterone levels. Foods high in zinc (like pumpkin seeds and lean meats), vitamin D (such as fatty fish and eggs), and healthy fats (like avocados and olive oil) support hormone production. Avoiding excessive sugar and processed foods can also help maintain stable testosterone levels.Sleep hygiene: Sleep is a powerful tool in hormone regulation. Testosterone production peaks during deep sleep, so it’s essential to prioritize quality rest. Aim for 7–9 hours of sleep each night, and ensure your sleep environment is conducive to deep, uninterrupted rest (i.e., keep it cool and dark).Manage stress: Chronic stress can significantly affect testosterone levels by increasing cortisol, a hormone that negatively impacts testosterone. Managing stress through practices like meditation, yoga, mindfulness, and sports can help lower cortisol levels and support healthy testosterone production.When to consider medical interventionWhile natural methods can help optimize testosterone levels, some men may need medical intervention. Testosterone replacement therapy (TRT) is a treatment option for those with significantly low testosterone levels, particularly when lifestyle changes are insufficient. TRT can improve energy, mood, and physical health by restoring testosterone to normal levels. Over the years, I have been truly fascinated by the profound impact it can have on men, often transforming their vitality, confidence, and overall well-being. However, it’s important to approach TRT with caution, as it comes with potential side effects, including benign prostate enlargement, mood swings, and increase in red blood cells. It’s essential to work closely with a healthcare provider to assess whether a TRT is appropriate for you, taking into account your individual health conditions and goals.Finding balanceThrough our work with hundreds of men, I have witnessed firsthand the profound impact that testosterone optimization can have, not just on energy, mood, and strength. I truly believe that testosterone plays a crucial role in how well we age, and there is much to be learned from its effects on long-term health. By maintaining optimal testosterone levels through natural lifestyle changes, you can significantly enhance your quality of life and potentially extend your health span. However, it’s essential to approach testosterone optimization with balance—too little can be detrimental, but too much can also have negative effects. In the end, maintaining healthy testosterone levels is just one piece of the longevity puzzle. A holistic approach that includes regular exercise, a nutrient-rich diet, stress management, and quality sleep is, in my view, the key to living a long, strong, and fulfilling life. 

Air Purifier

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3 min read

How particulate matter harms health and how air purifiers can help

Alright, so let's talk about PM2.5, those tiny air pollution particles, and how air purifiers might help. It's a pretty big deal, honestly, how these things mess with our health. Basically, PM2.5 are these super small particles, think 2.5 micrometers or less. To put that in perspective, a human hair is, like, 50-70 micrometers. These little guys can get deep into your lungs and even your bloodstream. Not great, right?Sources of fine particulate air pollutionThey come from a mix of natural and human sources. Naturally, you've got stuff like wildfires and volcanoes. But, yeah, humans aren't helping. Think industrial plants, car exhaust, even your home heating. To get a bit more specific, industrial processes like factories and power plants are major culprits, residential heating with wood-burning stoves and fireplaces contribute, transportation with cars and trucks, and construction and agriculture with dust from sites and fields.Health effectsAnd the health effects? Short-term, you might see increased blood pressure, messed-up blood sugar, and, yeah, it seems to make viruses, like COVID-19, worse. Long-term, we're talking heart disease, lung problems like asthma, chronic obstructive pulmonary disease (COPD), and even brain stuff, like lower IQ and potential links to ADHD and ASD in kids.It's serious. Also, let's be real, marginalized communities get hit harder. Systemic issues play a role, sadly. So prolonged exposure can significantly reduce overall longevity, particularly among vulnerable populations such as the elderly, children, and individuals with existing health issues.Air purifiers as a solution?So may air purifiers help? Do they actually do anything? Basically, yeah, they can. They suck in the air and run it through filters, usually HEPA filters. These HEPA filters are designed to catch those tiny PM2.5 particles. Activated carbon filters are also common, and they help with odors and gases. You'll find them at most big electronics stores, home improvement stores, and online. Examples for often recommended Brands are:BlueairCowayDysonHoneywellJasprTeqoyaThey offer improved respiratory health, especially for people in polluted areas or with conditions like asthma, and they can reduce allergens, too. There are portable ones, great for individual rooms, and whole-house ones, installed into your HVAC system to filter the air throughout your entire home. Look for certifications like AHAM and Energy Star.Okay, here's the skeptical part. Air purifiers have limitations. They only work well in the room they're in. You gotta replace the filters regularly, or they're useless. They might not get all gases and VOCs. Some purifiers can release ozone, which is bad. And proper use is key, placement matters. To maximize the effectiveness of an air purifier, proper placement is crucial. It is recommended to position the purifier in a central location within the room to ensure optimal air circulation. Choosing the appropriate size of an air purifier is essential for effective air cleaning. A unit that is too small for a large room will be ineffective, while one that is too large may waste energy and resources.Regular maintenance is key to keeping an air purifier functioning efficiently. Cleaning the pre-filter as recommended by the manufacturer can help capture larger particles and prolong the life of the main filter. For optimal results, air purifiers should be operated continuously, particularly in spaces with persistent air quality issues. To ensure that an air purifier is functioning effectively, users can monitor its airflow and check for consistent performance. Make sure that these points are taken into account, so you gain the maximum profit for your health and longevity.

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